客户专员：刘小姐

产品名称：sigma|b6179| 11076-19-0|bongkrekic acid solution|上海创赛

产品描述：

biochem/physiol actions

an antiapoptotic agent, it protects against  receptor induced neuronal apoptosis,- extends cell survival in cells undergoing apoptosis following infection with viral vectors and abrogates apoptosis induced by in t-cells. it is an inhibitor of adenine nucleotide translocase, which is a component of the mitochondrial permeability transition (mpt) pore complex. bongkrekic acid prevents mitochondrial depolarization, swelling, rupture of mitochondrial outer membrane, and release of apoptogenic proteins such as cytochrome c. this phenomenon was observed during staurosporine induced apoptosis in jurkat cells, in hepg2 undergoing apoptosis following tnf-α and ethanol.

other notes

the toxic principle of p. cocovenenans.

包装

0.5 mg in glass bottle

physical form

solution in 0.01 m tris buffer, ph 7.5.

features and benefits

this compound is a featured product for apoptosis research. click here to discover more featured apoptosis products. .

性质：

related categoriesa to c, adenine nucleotide translocase, apoptosis inhibitors, apoptosis and cell cycle, b,

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biological source  pseudomonas cocovenenans

inchi key          shcxabjsxuacku-wutqzgrksa-n

assay                  ≥95% (hplc)

concentr   ation  ~1 mg/ml

shipped in          wet ice

storage temp.   -20°c

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