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产品名称：Sigma|31395|9011-18-1|葡聚糖硫酸酯 钠盐 来源于明串珠菌 属|Dextran sulfate sodium salt from Leuconostoc spp.

产品描述：

Preparation Note

由 Mr 为 ~500,000 的葡聚糖制备

Application

Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions.[6] It has was used for releasing DNA from DNA-histone complexes.[3]

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.[1][5]The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

性质：

form          powder

mol wt   Mr ~500,000

composition   Sulfur Content, 16.0-19.0%

solubility   H2O: freely soluble 50 mg/mL, clear

anion traces   chloride (Cl-): ≤100 mg/kg

cation traces   Ca: ≤200 mg/kg

         Cd: ≤5 mg/kg

         Co: ≤5 mg/kg

         Cr: ≤5 mg/kg

         Cu: ≤5 mg/kg

         Fe: ≤5 mg/kg

         K: ≤1000 mg/kg

         Mg: ≤100 mg/kg

         Mn: ≤5 mg/kg

         Ni: ≤5 mg/kg

         Pb: ≤5 mg/kg

         Zn: ≤5 mg/kg

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