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产品名称：Sigma|D6392|75522-97-3|P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt

产品描述：

包装

10, 50 mg in poly bottle

Biochem/physiol Actions

A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap* is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.

性质：

Related Categories Enzyme Inhibitors, Enzyme Inhibitors by Type,                                 Substrate Analogs, 生化试剂, 酶、抑制剂和底物 Less...

InChI Key           BFBDFBHROZLGEG-JJCYRVQFSA-K

assay                   ≥95%

form                   powder

color                   white to off-white

solubility           H2O: 50 mg/mL

storage temp.          ?20°C

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