Product Information

Material Number: 550315

Size: 100 tests

Vol. per Test: 20 μl

Clone: P1H12

Isotype: Mouse IgG1, κ

Reactivity: QC Testing: Human

Workshop: NA

Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Description

Reacts with a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, Mel-CAM. CD146 is a member of the immunoglobulin 

superfamily and is expressed on endothelial cells, melanoma cells, smooth muscle, intermediate trophoblasts and has been reported as being 

present on a subpopulation of activated T cells. P1H12 monoclonal antibody has been reported to block endothelial cell adhesion and has been 

observed very early in embryogenesis. It can be useful in the study of embryologic vasculogenesis. This antibody is suitable for 

immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA.

Preparation and Storage

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.

Application Notes

Application

Flow cytometry               Routinely Tested

Suggested Companion Products

Catalog Number  Name                                        Size             Clone

555749             PE Mouse IgG1, κ Isotype Control  100 tests     MOPC-21

Product Notices

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.