Z-LEHD-FMK, Caspase-9 Inhibitor

Product Information

Material Number: 550381

Size: 1.0 mg

Description

Members of the caspase family play key roles in inflammation and mammalian apoptosis. Z-LEHD-FMK is an irreversible and cell permeable inhibitor of caspase-9. The peptide is O-methylated in the P1 position on aspartic acid providing enhanced stability and increased cell permeability. Z-LEHD-FMK can be used to inhibit primarily caspase-9 activity and to study events downsteam of caspase-9 activation. Z-LEHD-FMK has been reported to have a molecular weight of 804 Daltons.

Preparation and Storage

Avoid multiple freeze-thaws of product.

Z-LEHD-FMK, Caspase-9 Inhibitor is provided as a lyophilized powder. Store the lyophilized inhibitor at -20?C. Reconstitute the inhibitor in DMSO before use. The reconstituted inhibitor may be stored in small aliquots at -20?C.

Application Notes

Application

Flow cytometry                   Routinely Tested

Suggested Companion Products

Catalog Number  Name                                               Size        Clone

559763             PE Annexin V Apoptosis Detection Kit I 100 tests (none)

Product Notices

 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results results.